In C. elegans , neurodegeneration induced by excitotoxicity or aggregation of misfolded proteins is dependent on genes involved in calcium release from the endoplasmic reticulum. Reactive oxygen
This pipeline was created with the open-source software CellProfiler (4.2.1 release) and it is suitable for the automatized analysis of confocal microscopy images, allowing the quantification of the l
Arrows signify whether the epithelial, mesenchymal or knockdown phenotypes are associated with a significant increase (↑) or decrease (↓) or no change (↔) in Ca2+ influx via each pathway. Changes in t