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Subacute oral glyphosate induces dose-dependent renal injury in male mice (Mus musculus): per-animal data, analysis code and results

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Zenodo2026-06-27 更新2026-06-28 收录
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This record contains the complete underlying data, analysis code and derived results for the study "Subacute oral glyphosate induces dose-dependent renal injury in male mice (Mus musculus)". Adult male mice (n = 10/group) received vehicle or technical-grade glyphosate at 10, 50 or 100 mg/kg/day by oral gavage for 28 days. Endpoints measured in the same 40 animals: serum renal-function markers and electrolytes, renal oxidative-stress markers (MDA, GSH, SOD, CAT) and haematoxylin-eosin histopathology. Files: S1 per-animal raw data; S2 Python analysis code reproducing all reported statistics (ANOVA/Tukey, Kruskal-Wallis/Dunn, Jonckheere-Terpstra trend, BH-FDR, correlations, benchmark-dose modelling, and Welch/Games-Howell and cage-level sensitivity analyses); S3 supplementary tables; S4 cleaned summary results; requirements.txt; README. Run: pip install -r requirements.txt, then python S2_Statistical_code.py. Associated article submitted to Drug and Chemical Toxicology (Taylor & Francis), 2026.

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2026-06-27
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