Dendrimer-targeted immunosuppression of microglia reactivity further enhances promotes photoreceptor regeneration kinetics in the zebrafish retina

We used a zebrafish model of inducible rod photoreceptor death and investsgate the effect of Dexamethasone and nanoparticle-conjugated Dex on regeneration kinetics Overall design: We used bulk-RNA seq to analyze expression of zebrafish eyes at 7 days old that were untreated, treated with Mtz (to kill rods), treated with Mtz + D-Dex (induce immunosupression) or treated with D-Dex alone