Inhibition of Mitochondria NADH–Ubiquinone Oxidoreductase (Complex I) Sensitizes the Radioresistant Glioma Cells to Radiation. Inhibition of Mitochondria NADH–Ubiquinone Oxidoreductase (Complex I) Sensitizes the Radioresistant Glioma Cells to Radiation

We cumulatively radiated a glioblastoma cell line, U87MG, and screened radioresistant glioma cells. A transcriptome sequencing was performed to analyze the transcription differences between the raidoresistant and control cells. Overall design: U87MG cells (1×10^6) in 10 cm culture dishes were irradiated them with 2 Gy of X-rays for 5 times. The radioresistant U87MG cells were named as U87MG_F. The U87MG and U87MG_F cells were perfomred RNA sequencing through Illumina Hiseq xten Sequencing.