Shotgun proteomics of Sparus aurata hepatic stress response

This study characterizes the liver stress proteome of fish submitted to overcrowding (OC), repeated net-handling (NET) and hypoxia (HYP). Fish trials were conducted in triplicate tanks and two fish per tank were randomly sampled for MS analysis. This work aims to disclose most significant changes in signaling and metabolic pathways involved in the stress response. This data-driven knowledge may ultimately contribute for the improvement of species-specific welfare management protocols, towards a sustainable aquaculture.