Expression data from murine hematopoietic stem cells isolated from mice treated with control oil or estradiol. Mus musculus

The division rate of hematopoietic stem cells (HSCs) are promoted by estradiol. To identify the mechanism by which estradiol regulates HSCs, we performed gene expresssion profiling of HSCs isolated from mice of both sexes treated with either control vehicle (oil) or estradiol for one week. Overall design: 4 groups were analyzed; 1) HSCs from male mice treated with oil, 2) HSCs from male mice treated with estradiol, 3) HSCs from female mice treated with oil, and 4) HSCs from female mice treated with estradiol. All groups include 3 biological replicates isolated from 3 mice.