Group deposition of ZIKV NS2B-NS3 protease in complex with inhibitors from ASAP Discovery Consortium -- Crystal Structure of ZIKV NS2B-NS3 protease in complex with ASAP-0022474-001

Group deposition of ZIKV NS2B-NS3 protease in complex with inhibitors from ASAP Discovery Consortium -- Crystal Structure of ZIKV NS2B-NS3 protease in complex with ASAP-0022474-001 Descriptor: (4S)-N-[3-(aminomethyl)phenyl]-2-[(pyrrolidin-1-yl)methyl]imidazo[1,2-a]pyridine-8-carboxamide, DIMETHYL SULFOXIDE, Serine protease NS3, ... Authors: Ni, X, Marples, P.G, Godoy, A.S, Koekemoer, L, Aschenbrenner, J.C, Balcomb, B.H, Fairhead, M, Lithgo, R.M, Lee, A, Kenton, N, Thompson, W, Tomlinson, C.W.E, Wild, C, Winokan, M, Williams, E.P, Chandran, A.V, Walsh, M.A, Fearon, D, von Delft, F. Deposit date: 2025-04-10 Release date: 2025-04-23 Last modified: 2026-02-18 Method: X-RAY DIFFRACTION (1.721 Å) Cite: Group deposition of ZIKV NS2B-NS3 protease in complex with inhibitors from ASAP Discovery Consortium To Be Published

ASAP发现联盟来源的寨卡病毒（ZIKV）NS2B-NS3蛋白酶-抑制剂复合物集体提交——寨卡病毒NS2B-NS3蛋白酶与ASAP-0022474-001复合物的晶体结构
描述：(4S)-N-[3-(氨甲基)苯基]-2-[(1-吡咯烷基)甲基]咪唑并[1,2-a]吡啶-8-甲酰胺、二甲基亚砜、丝氨酸蛋白酶NS3
作者：Ni, X、Marples, P.G、Godoy, A.S、Koekemoer, L、Aschenbrenner, J.C、Balcomb, B.H、Fairhead, M、Lithgo, R.M、Lee, A、Kenton, N、Thompson, W、Tomlinson, C.W.E、Wild, C、Winokan, M、Williams, E.P、Chandran, A.V、Walsh, M.A、Fearon, D、von Delft, F.
沉积日期：2025-04-10
发布日期：2025-04-23
最后修改日期：2026-02-18
实验方法：X射线衍射（分辨率1.721埃）
引用：ASAP发现联盟来源的寨卡病毒NS2B-NS3蛋白酶-抑制剂复合物集体提交 待发表