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Structure of the C-terminal Domain of RAGE and Its Inhibitor

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Protein Data Bank Japan2026-02-25 更新2026-04-04 收录
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Structure of the C-terminal Domain of RAGE and Its Inhibitor Descriptor: 4-[(morpholin-4-yl)methyl]-2-{4-[(2R)-5-oxopyrrolidin-2-yl]phenyl}quinoline-7-carbonitrile, Advanced glycosylation end product-specific receptor Authors: Theophall, G.G, Ramasamy, R, Schmidt, A.M, Manigrasso, M, Shekthman, A. Deposit date: 2024-08-09 Release date: 2025-08-13 Last modified: 2026-02-25 Method: SOLUTION NMR Cite: RAGE-mediated activation of the formin DIAPH1 and human macrophage inflammation are inhibited by a small molecule antagonist. Cell Chem Biol, 32, 2025
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2024-08-09
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