Data_Sheet_1_Mental Health Among Medical Students During COVID-19: A Systematic Review and Meta-Analysis.docx

BackgroundThe mental health of medical students is an issue worthy of attention, especially during COVID-19. Many studies have shown that depression and anxiety are the main problems faced by medical students. To assess the pooled prevalence of depression and anxiety among medical students worldwide, we conducted this meta-analysis.MethodsAccording to PRISMA, we used a computerized strategy to search studies in EMBASE, PubMed, PsycArticles, Web of Science, and China Biology Medicine disc. The pooled prevalence of depression and anxiety was calculated by a random-effects model. Heterogeneity was explored by subgroup analysis. Sensitivity analysis and publication bias were also carried out in this meta-analysis.ResultsOf 1316 studies, 41 studies were selected based on 36608 medical students. The pooled depression prevalence was 37.9% (95% CI: 30.7–45.4%), and pooled anxiety prevalence was 33.7% (95% CI: 26.8–41.1%). The prevalence of depression and anxiety among medical students varied by gender, country, and continent.ConclusionThe data reported that the prevalence of depression and anxiety among medical students during COVID-19 was relatively higher than those of the general population and the healthcare workers. The impact of COVID-19 on medical students and how to protect the mental health of medical students are needed to determine through further research.Systematic Review Registration[https://www.crd.york.ac.uk/prospero/display_record.php?ID=CRD42021274015], identifier [CRD42021274015].

背景：医学生的心理健康问题备受关注，尤其是在COVID-19疫情期间。众多研究表明，抑郁和焦虑是医学生面临的主要心理问题。为评估全球医学生中抑郁和焦虑的合并患病率，本研究进行了系统评价。方法：依据PRISMA指南，本研究采用计算机搜索策略，在EMBASE、PubMed、PsycArticles、Web of Science和中国生物医学文献数据库中检索相关研究。采用随机效应模型计算抑郁和焦虑的合并患病率。通过亚组分析探讨异质性。此外，本系统评价还进行了敏感性分析和发表偏倚分析。结果：从1316项研究中筛选出41项，涉及36608名医学生。合并抑郁患病率为37.9%（95%CI：30.7–45.4%），合并焦虑患病率为33.7%（95%CI：26.8–41.1%）。医学生中抑郁和焦虑的患病率在不同性别、国家和洲际间存在差异。结论：数据显示，COVID-19期间医学生的抑郁和焦虑患病率相对高于普通人群和医护人员。需要进一步研究以确定COVID-19对医学生的影响以及如何保护医学生的心理健康。系统评价注册信息：[https://www.crd.york.ac.uk/prospero/display_record.php?ID=CRD42021274015]，标识符：[CRD42021274015]。