TNF-NFkB-p53 axis restricts in vivo survival of hPSC-derived dopamine neuron

NIAID Data Ecosystem2026-05-02 收录

多巴胺神经元

帕金森病细胞治疗

数据链接：

https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE216365 数据链接链接失效反馈

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This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

创建时间：

2024-07-26

Effects of sialidase and GM1 ganglioside administration on unilateral substantia nigra pars compacta dopamine neuron cell counts.

多巴胺神经元

神经药物

a P < 0.001 vs. aCSF/Saline b P < 0.01 vs aCSF-MPTP c P < 0.0001 vs. Normal/Saline d P < 0.0001 vs. MPTP/Saline. Data shown are mean ± SEM. Effects of sialidase and GM1 ganglioside administration on u

NIAID Data Ecosystem60

Dopamine Neuron Stimulating Actions of a GDNF Propeptide

帕金森病治疗肽段

多巴胺神经元

BackgroundNeurotrophic factors, such as glial cell line-derived neurotrophic factor (GDNF), have shown great promise for protection and restoration of damaged or dying dopamine neurons in animal model

NIAID Data Ecosystem60

Therapeutic effects of human neural progenitor cells derived from placental fibroblasts induced by small molecule compounds under normoxia on Parkinson's disease rat models

帕金森病细胞治疗

化学重编程神经祖细胞

Human fibroblasts can be reprogrammed into ciNPCs using a chemical cocktail under normoxia. Compared with endogenous NPCs, these ciNPCs have similar characteristics in terms of cellular properties, se

NIAID Data Ecosystem20

Hypoxia Promotes Dopaminergic Differentiation of Mesenchymal Stem Cells and Shows Benefits for Transplantation in a Rat Model of Parkinson’s Disease

干细胞分化

帕金森病细胞治疗

Mesenchymal stem cells (MSCs) are multipotent cells capable of differentiating into dopaminergic (DAergic) neurons, which is one of the major cell types damaged in Parkinson’s disease (PD). For this r

NIAID Data Ecosystem60

中脑多巴胺神经元过度激活研究数据

神经科学

多巴胺神经元

本数据集为论文“Chronic hyperactivation of midbrain dopamine neurons causes preferential dopamine neuron degeneration”的原始数据，记录了中脑多巴胺神经元慢性过度激活相关的实验数据，用于支持该研究的核心结论。数据集仅包含一个文件。论文“Chronic hyperactivation of midb

海数据50

TNF-NFkB-p53 axis restricts in vivo survival of hPSC-derived dopamine neuron

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