Ipilimumab-induced side effects of the endrocrine system.

*case is detailed in the result section. alisted treatments are systemic treatments unless otherwise specified. btumor-free high-risk stage III melanoma (AJCC 2009); adjuvant administration of ipilimumab. cstage IV metastatic disease (AJCC 2009). dlimb perfusion with melphalan. M indicates male; F, female; LN, lymph nodes; IFN-α, interferon-α; DTIC, dacarbazine; GIT, gastrointestinal tract; IGF-1, insulin-like growth factor-1; TSH, thyroid-stimulating hormone; PR, partial response; SD, stable disease; PD, progressive disease; MR, mixed response.