Determination by systematic deletion of the amino acids essential for catalysis by ricin A chain.
收藏PubMed Central1992-06-01 更新2026-05-16 收录
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https://pmc.ncbi.nlm.nih.gov/articles/PMC49189/
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资源简介：
The A chain of ricin is a RNA N-glycosidase that inactivates ribosomes by depurination of a single adenosine in 28S rRNA. Of the 267 amino acids in the protein, 222 (83%) could be deleted from one or another of 74 mutants without loss of the capacity of the protein to recognize a single nucleotide from among the 7000 in ribosomes or to catalyze hydrolysis. IMAGES:
提供机构：
National Academy of Sciences
创建时间：
1992-06-01
