TMEM106B(120-254) T185S singlet amyloid fibril from frontotemporal lobar degeneration with TDP-43 pathology (FTLD-TDP) type B case 2 (case 7).

TMEM106B(120-254) T185S singlet amyloid fibril from frontotemporal lobar degeneration with TDP-43 pathology (FTLD-TDP) type B case 2 (case 7). Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Transmembrane protein 106B Authors: Fitzpatrick, A.W.P, Stowell, M.H.B, Chang, A, Xiang, X, Wang, J, Lee, C, Arakhamia, T, Simjanoska, M, Wang, C, Carlomagno, Y, Zhang, G, Dhingra, S, Thierry, M, Perneel, J, Heeman, B, Forgrave, L.M, DeTure, M, DeMarco, M.L, Cook, C.N, Rademakers, R, Dickson, D, Petrucelli, L, Mackenzie, I.R.A. Deposit date: 2022-02-19 Release date: 2022-03-23 Last modified: 2025-05-28 Method: ELECTRON MICROSCOPY (3 Å) Cite: Homotypic fibrillization of TMEM106B across diverse neurodegenerative diseases. Cell, 185, 2022本数据集样本为TMEM106B(120-254) T185S单体淀粉样原纤维，取自伴TDP-43病理的额颞叶变性（frontotemporal lobar degeneration with TDP-43 pathology, FTLD-TDP）B型病例2（病例7）。 描述项：2-乙酰氨基-2-脱氧-β-D-吡喃葡萄糖、跨膜蛋白106B（Transmembrane protein 106B） 作者：Fitzpatrick, A.W.P、Stowell, M.H.B、Chang, A、Xiang, X、Wang, J、Lee, C、Arakhamia, T、Simjanoska, M、Wang, C、Carlomagno, Y、Zhang, G、Dhingra, S、Thierry, M、Perneel, J、Heeman, B、Forgrave, L.M、DeTure, M、DeMarco, M.L、Cook, C.N、Rademakers, R、Dickson, D、Petrucelli, L、Mackenzie, I.R.A. 存放日期：2022-02-19 发布日期：2022-03-23 最后修改日期：2025-05-28 检测方法：电子显微镜（3 Å） 引用文献：《跨多种神经退行性疾病的TMEM106B同源原纤维形成》，《细胞》，185卷，2022年