Mycobacterial CIII2CIV2 supercomplex, inhibitor free, -Lpqe cyt cc open

Mycobacterial CIII2CIV2 supercomplex, inhibitor free, -Lpqe cyt cc open Descriptor: (2R)-2-(hexadecanoyloxy)-3-{[(S)-hydroxy{[(1R,2R,3R,4R,5R,6S)-2,3,4,5,6-pentahydroxycyclohexyl]oxy}phosphoryl]oxy}propyl (9S)-9-methyloctadecanoate, (2R)-3-(((2-aminoethoxy)(hydroxy)phosphoryl)oxy)-2-(palmitoyloxy)propyl (E)-octadec-9-enoate, (2S)-1-(hexadecanoyloxy)propan-2-yl (10S)-10-methyloctadecanoate, ... Authors: Di Trani, J.M, Yanofsky, D.J, Rubinstein, J.L. Deposit date: 2021-07-16 Release date: 2021-08-04 Last modified: 2024-11-06 Method: ELECTRON MICROSCOPY (3.5 Å) Cite: Structure of mycobacterial CIII 2 CIV 2 respiratory supercomplex bound to the tuberculosis drug candidate telacebec (Q203). Elife, 10, 2021分枝杆菌CIII₂CIV₂超级复合物，无抑制剂，-Lpqe细胞色素cc开放状态 结构描述：(2R)-2-(十六烷酰氧基)-3-{[(S)-羟基{[(1R,2R,3R,4R,5R,6S)-2,3,4,5,6-五羟基环己基]氧基}磷酰基]氧基}丙基(9S)-9-甲基十八烷酸酯、(2R)-3-(((2-氨基乙氧基)(羟基)磷酰基)氧基)-2-(棕榈酰氧基)丙基(E)-十八碳-9-烯酸酯、(2S)-1-(十六烷酰氧基)丙-2-基(10S)-10-甲基十八烷酸酯等 作者：Di Trani, J.M.、Yanofsky, D.J.、Rubinstein, J.L. 存档日期：2021-07-16 发布日期：2021-08-04 最后修改日期：2024-11-06 研究方法：电子显微镜（分辨率3.5 Å） 引用文献：《结合结核病候选药物telacebec（Q203）的分枝杆菌CIII₂CIV₂呼吸超级复合物的结构》，《eLife》，第10卷，2021年