five

Gene activation guided by nascent RNA-bound transcriptional factors

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NIAID Data Ecosystem2026-03-14 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE204666
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Purpose: To identify differential expressed genes after Narta activation Methods: cell lines with gene of interest inserted with TriTag were activated by Narta and then collected for RNA sequencing at 48 hpf (hours post Narta activation) Results: We found 1 and 2 (overlapped) up-regulated genes in HSPB8 and LMNA respectivelly at 48 hpf (FDR < 0.05, log2 fold change > 2) Conclusions: Narta is an activation system with high specificity comparison of tanscriptome between control and activation group at 48 hpf
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2022-12-15
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