Human Proteome Map

The Human Proteome Map (HPM) portal integrates the peptide sequencing result from the draft map of the human proteome project. The project was based on LC-MS/MS by utilizing of high resolution and high accuracy Fourier transform mass spectrometry. The HPM contains direct evidence of translation of a number of protein products derived from human genes, based on peptide identifications of multiple organs/tissues and cell types from individuals with clinically defined healthy tissues. The HPM portal provides data on individual proteins, as well as on individual peptide spectra. This collection references proteins.

人类蛋白质组图谱（HPM）门户整合了人类蛋白质组计划草案图谱中的肽段测序结果。该项目基于液相色谱-串联质谱（LC-MS/MS）技术，采用高分辨率和高精度傅里叶变换质谱仪。HPM包含了由人类基因衍生的多种蛋白质产物翻译的直接证据，这些证据基于对具有临床定义的健康组织的个体多个器官/组织和细胞类型的肽段鉴定。HPM门户提供了关于单个蛋白质及其单个肽段光谱的数据。本收集涉及蛋白质。

搜集汇总

背景与挑战

背景概述

Human Proteome Map是一个基于高分辨率质谱技术的人类蛋白质组交互式数据库，整合了来自30个健康组织、细胞类型和胎儿样本的肽段测序数据，直接验证了超过17,000个人类基因的蛋白质表达，覆盖了84%以上的已注释蛋白质编码基因。该数据集包含超过290,000个非冗余肽段鉴定，提供了蛋白质组学的定量和选择性反应监测信息，支持大规模生物医学研究。