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The effects of antimigratory drugs lithium chloride and 6-bromoindirubin-3'-oxime (BIO) in glioblastoma cells

ChEBI2023-03-20 更新2026-07-12 收录

胶质母细胞瘤药物研究

癌细胞迁移

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https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-MTAB-12775 数据链接链接失效反馈

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The effects of antimigratory drugs lithium chloride and 6-bromoindirubin-3'-oxime (BIO) in glioblastoma cells

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2023-03-20

癌细胞迁移

Yap信号通路

Biophysical features of the microenvironment such as stiffness of extracellular matrix (ECM), nanotopography, and biomechanical force are critical regulators of cellular potential and behavior, yet th

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Table4_Tizoxanide Promotes Apoptosis in Glioblastoma by Inhibiting CDK1 Activity.docx

胶质母细胞瘤药物研究

CDK6抑制机制

The antiparasitic drug nitazoxanide (NTZ) has received considerable attention for its potential in cancer therapy. In this study, we demonstrate that tizoxanide (TIZ), an active metabolite of NTZ, exh

NIAID Data Ecosystem30

Gene expression of 5-azacytidine-treated HCT116 cells. Gene expression of 5-azacytidine-treated HCT116 cells

甲基化调控基因

癌细胞迁移

DNA methylation plays an important role in regulating gene expression. In this study, a subpopulation with accelerated baseline motility (MG cells) or an immotile one (non-MG cells) from a colon cance

NIAID Data Ecosystem30

High-throughput 3D glioblastoma model for rapid personalized therapeutic screening

胶质母细胞瘤药物研究

个性化医疗

Glioblastoma (GBM) is a devastating brain tumor with limited therapeutic success, largely due to the inability to pre-test patient-specific responses to treatment in a reliable and timely manner with

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Identification of Parthenolide Dimers as Activators of Pyruvate Kinase M2 in Xenografts of Glioblastoma Multiforme in Vivo

胶质母细胞瘤药物研究

PKM2

Herein we detail the discovery of a series of parthenolide dimers as activators of PKM2 and evaluation of their anti-GBM activities. The most promising compound 5 showed high potency to activate PKM2

Figshare2020-01-24 更新30

The effects of antimigratory drugs lithium chloride and 6-bromoindirubin-3'-oxime (BIO) in glioblastoma cells

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