Expression data from Chronic Unpredict Mild Stress-induced depression in GK rats‘ liver. Rattus norvegicus

To explored the mechanism of pharmacokinetic perturbation in chronic unpredicted mild stress (CUMS) resulting depression, CUMS-induced depression animal model with spontaneous diabetic GK rats were established. The expression profile in GK rats' livers were screened using Affymetrix Rat 230 2.0 Array. Overall design: Male GK rats emergenced of diabetes symptom, then were randomly divided into two groups: control group and CUMS group. Rats were sacrificed after 8 weeks' CUMS resulting in depression. Rat’s livers were selected for RNA extraction and hybridization on Affymetrix microarrays.