DNA replication occurs in a defined temporal order known as the replication-timing (RT) program. RT is regulated during development in discrete chromosomal units, coordinated with transcriptional acti
Supplementary data for the article "CTCF mediated genome architecture regulates the dosage of mitotically stable mono-allelic expression of autosomal genes" by Chandradoss et al
H3K9me3-dependent heterochromatin is critical for the silencing of repeat-rich pericentromeric regions and also has key roles in repressing lineage-inappropriate protein-coding genes for healthy cellu