Jnk1 complexed with a bis-anilino-pyrrolopyrimidine inhibitor.
收藏Protein Data Bank Japan2023-09-06 更新2026-03-21 收录
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资源简介：
Jnk1 complexed with a bis-anilino-pyrrolopyrimidine inhibitor. Descriptor: 2-fluoro-6-{[2-({2-methoxy-4-[(methylsulfonyl)methyl]phenyl}amino)-7H-pyrrolo[2,3-d]pyrimidin-4-yl]amino}benzamide, Mitogen-activated protein kinase 8 Authors: Chamberlain, S, Atkins, C, Deanda, F, Dumble, M, Gerding, R, Groy, A, Korenchuk, S, Kumar, R, Lei, H, Mook, R, Moorthy, G, Redman, A, Rowland, J, Shewchuk, L, Vicentini, G, Mosley, J. Deposit date: 2008-09-22 Release date: 2008-12-30 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Optimization of 4,6-bis-anilino-1H-pyrrolo[2,3-d]pyrimidine IGF-1R tyrosine kinase inhibitors towards JNK selectivity. Bioorg.Med.Chem.Lett., 19, 2009
创建时间：
2008-09-22
