Polymorphims of <i>M. tuberculosis</i> strains of Beijing genotype.

Isolates are grouped into 11 arbitrary sublineages on the basis of the polymorphisms relative to genomic deletion RD105, RD181, RD150 and RD142, RV3135 IS1547 RFLP pattern and mutations in genes mutT4 and mutT2. apresence (+) or absence (−) of the specific genomic region. bpresence (+) or absence (−) of the specific mutation. cspoligotype international type. dsublineage 1: a 0.15-kb PCR product, sublineage 2–4: “atypical” isolates, with a 1.97-kb PCR product, sublineage 5–11: “typical” isolates, with a 1.02-kb PCR product. epattern 1: three bands (1.7, 2.1, and 2.5 kb), pattern 2: two bands (2.1 and 2.5 kb), pattern 3–7: individual patterns, all containing the 2.5 kb band, except pattern 8 that has no 2.5 kb band.