Ebola virus delta peptide is an enterotoxin

Transcriptomic analyses showed that Ebola virus delta peptide triggers damage response and cell survival pathways. Delta peptide also downregulates the expression of transporters and exchangers that mediate absorption of ions, sugars, and small chain fatty acids. Overall design: Ligated ileal loops instilled with either buffer or a synthetic peptide representing the active portion of Ebola virus delta peptide, resected at 6 and 9 hours after surgery and subjected to RNA-Seq analysis