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Study of FK866 against T-cell acute lymphoblastic leukemia.

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NIAID Data Ecosystem2026-05-02 收录
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Novel agents targeting upregulated signaling pathways are needed to improve outcomes in T-cell acute lymphoblastic leukemia (T-ALL), since conventional cytotoxic chemotherapy regimens have reached the limits of tolerability. We identified upregulated, targetable signaling pathways common to both human T-ALL samples and a KrasLSL-G12D/+.Mb1Cre/+ murine model of T-ALL.

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2025-03-11
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