Expression analysis of circadian light response in Drosophila. Drosophila melanogaster

Light is a strong environmental cue that resets the circadian clock rhythm. We have used Affymetrix microarrays to profile the Drosophila head transcriptome response following a brief light pulse during the early night. Comparison of control (un-pulsed) and experimental flies reveal large number of differentially expressed transcripts underlying the process of light entrainment of the clock. Overall design: Wild type flies exposed to light pulse at ZT15 compared to control group (no pulse)