Supporting information.

Selection of sample for sRAGE analyses (Fig A). Selection of sample for genetic association analyses (Fig B). AGER SNP identifiers (Table A). Power calculations for analyses of AGER SNPs and clinical outcomes (Table B). Bivariate associations with sRAGE levels (N = 2329) (Table C). Additional genome-wide significant loci and corresponding trans-ethnic results for sRAGE levels in whites and blacks (Table D). Characteristics of participants with sRAGE levels and participants included in analyses of clinical outcomes (Table E). (DOCX)