Single cell RNA Seq of cortex cells from adult human ovaries

In this study, human ovarian cortex was characterised on a transcriptional level. Major questions concerned the differences of cortical cell type composition in ovaries donated by Cesarian section and gender reassignment patients, respectively, as well as the presence of putative oogonial stem cells or germline-like cells. Furthermore, comparison to and integration of the scRNA-Seq dataset of human ovarian inner tissue (as compared to the outer cortex) published in 2019 was performed in order to obtain a complete picture of the adult human ovary on a cellular level.