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Stereoselective Furan-Iminium Cation Cyclization in the Construction of the Core Structure of Manzamine A

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NIAID Data Ecosystem2026-03-06 收录
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A new type of furan-iminium cation cyclization was developed and used to construct the ABC ring of manzamine A. The cyclization proceeded at the 2-position with complete regio- and stereoselectivity to give a spiro-center. The product was efficiently converted to the highly substituted core structure of manzamine A.

创建时间:
2016-05-05
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