The crystal structure of JAK2 in complex with Compound 31
收藏Protein Data Bank Japan2024-11-13 更新2026-04-25 收录
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The crystal structure of JAK2 in complex with Compound 31 Descriptor: 1,2-ETHANEDIOL, DIMETHYL SULFOXIDE, Tyrosine-protein kinase JAK2, ... Authors: Miller, S.T, Ellis, D.A. Deposit date: 2023-02-18 Release date: 2023-06-21 Last modified: 2024-11-13 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Eyes on Topical Ocular Disposition: The Considered Design of a Lead Janus Kinase (JAK) Inhibitor That Utilizes a Unique Azetidin-3-Amino Bridging Scaffold to Attenuate Off-Target Kinase Activity, While Driving Potency and Aqueous Solubility. J.Med.Chem., 66, 2023
创建时间:
2023-02-18



