The rectal mucosa is a critical site of HIV vulnerability. We sought to identify transcriptomic features of rectal mucosal tissue prior to exposure associated with support or restriction of HIV replic
Airway epithelial cells are crucial for mucosal and adaptive immunity as they produce mucins that trap and clear inhaled particulates by mucociliary activity, and also secrete diverse inflammatory med
This experiment was designed to explore the transcriptional programs of ?dT17 and ?dT1 cells isolated from the lamina propria and peripheral lymph nodes. For this purpose, we sorted intestinal ?dT17 (
The molecular mechanisms involved in host pathogen interactions at mucosal surfaces needs to be better understood in order to develop immune-mediated methods of protection against pathogens. Cholera t
The epithelium of the intestine functions as the primary “frontline” physical barrier for protection from enteric microbiota. Intraepithelial lymphocytes (IELs) distributed along the intestinal epithe
