Genome-scale analysis of aberrant DNA methylation in colorectal cancer. Homo sapiens
收藏NIAID Data Ecosystem2026-03-07 收录
下载链接：
https://www.ncbi.nlm.nih.gov/bioproject/PRJNA134727
下载链接
链接失效反馈官方服务：
资源简介：
To characterize DNA methylation-based subgroups in colorectal cancer, we performed genome-scale DNA methylation profiling of 125 colorectal tumor samples and 29 histologically normal-adjacent colonic tissue samples using the Illumina Infinium DNA methylation assay, which assesses the DNA methylation status of 27,578 CpG sites located at the promoter regions of 14,495 protein-coding genes. We identified four DNA methylation-based subgroups of CRC using model-based cluster analyses. Each subtype shows characteristic genetic and clinical features, indicating that they represent biologically distinct subgroups. Overall design: Bisulfite converted DNA from fresh frozen 125 colorectal tumors and 29 adjacent normal tissues were hybridized to the Illumina Infinium 27k Human Methylation Beadchip v1.2
创建时间：
2011-06-03
