Crystal structure of USP7 in complex with a 4-hydroxypiperidine based inhibitor
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Crystal structure of USP7 in complex with a 4-hydroxypiperidine based inhibitor Descriptor: 3-[[4-oxidanyl-1-[(3~{R})-3-phenylbutanoyl]piperidin-4-yl]methyl]-6-(2-pyrrolidin-1-ylethylamino)pyrimidin-4-one, GLYCEROL, SULFATE ION, ... Authors: Harrison, T, Gavory, G, O'Dowd, C, Helm, M, Flasz, J, Dossang, A, Hughes, C, Cassidy, E, McClelland, K, Odrzywol, E, Page, N, Barker, O, Miel, H, Feutron-Burton, S, Rountree, J.S.S. Deposit date: 2017-12-01 Release date: 2018-04-11 Last modified: 2024-05-08 Method: X-RAY DIFFRACTION (2.16 Å) Cite: Identification and Structure-Guided Development of Pyrimidinone Based USP7 Inhibitors. ACS Med Chem Lett, 9, 2018
创建时间：
2017-12-01
