PETAL Repository of Electronic Data COVID-19 Observational Study (RED CORAL)

To describe characteristics, treatment, and outcomes among patients hospitalized with COVID-19 early in the pandemic, 1480 consecutive adult inpatients with laboratory-confirmed, symptomatic SARS-CoV-2 infection admitted to 57 US hospitals from March 1 to April 1, 2020 were studied.It was found that in a geographically diverse early-pandemic COVID-19 cohort with complete hospital folllow-up, hospital mortality was associated with older age, comorbidity burden, and male sex. Intensive care unit admissions occurred early and were associated with protracted hospital stays. Survivors often required new health care services or respiratory support at discharge.The PETAL Network central institutional review board at Vanderbilt University and the institutional review boards at each participating hospital approved the study or determined that the study was exempt from review. Instructions for requesting individual-level data are available on BioData Catalyst at https://biodatacatalyst.nhlbi.nih.gov/resources/data/. Apply for data access in dbGaP. Upon approval, users may begin accessing requested data in BioData Catalyst. For questions about availability, you may contact the BioData Catalyst team at https://biodatacatalyst.nhlbi.nih.gov/contact.]]> Inclusion Criteria: Patients aged 18 years or older admitted to a study hospital from March 1 to April 1, 2020, were eligible for inclusion if they had a positive polymerase chain reaction test result for SARS-CoV-2 during their admission or within the preceding 14 days and exhibited clinical or radiological evidence of acute infection (including fever, cough, dyspnea, hypoxemia, or bilateral airspace opacities). Exclusion Criteria: prisoners and patients with prior hospital admission for COVID-19]]> The 57 geographically diverse hospitals participating in this retrospective cohort study were members of the NHLBI-sponsored PETAL Network.The PETAL Network central institutional review board at Vanderbilt University and the institutional review boards at each participating hospital approved the study or determined that the study was exempt from review ]]>