Supplementary Material for: Primary aquagenic pruritus successfully treated by β-alanine: A case report.

Aquagenic pruritus is a chronic debilitating itchy skin condition triggered by water exposure with limited treatment options. Here we present a case of primary aquagenic pruritus in an adult male who was successfully treated with β-alanine. Treatment efficacy was maintained at 20-weeks follow-up. This study includes a discussion of the pharmacodynamics of β-alanine and provides an insight into the pathophysiology of aquagenic pruritus. This study adds to the body of evidence supporting a role for β-alanine as an efficient and safe treatment option in patients with aquagenic pruritus.