We performed CRISPR screens on both a sub-library and a genome-wide scale in human intestinal organoids to discover cancer driver genes. We investigated the Wnt and the TGFB pathway and used both WT,

NIAID Data Ecosystem30

Additional file 2: of Frequent mutations in acetylation and ubiquitination sites suggest novel driver mechanisms of cancer

癌症驱动基因

蛋白质翻译后修饰

CCDS longest isoform sequences in FASTA format. (FASTA 10762 kb)

NIAID Data Ecosystem80

Additional file 4 of Gsw-fi: a GLM model incorporating shrinkage and double-weighted strategies for identifying cancer driver genes with functional impact

癌症驱动基因

基因组功能突变分析

Additional file 4. Table S3: The ratios of harmful mutations for driver genes identified by GSW-FI in 31 datasets.

Figshare2024-08-18 更新50

GATA2 as a potential prostate cancer metastasis-driving gene

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