RNAseq analysis of brown adipose tissue (BAT) and thyroid of new-born lambs, subjected to short-term cold exposure, reveals signs of early whitening of BAT

An RNA-seq approach was utilized to characterise the transcriptome of brown adipose tissue and thyroid tissue in new-born Romney lambs after a short exposure (2 days) to cold conditions. This study provides an in-depth expression network of the main characters involved in thermogenesis and fat whitening mechanisms that take place in the new-born lamb. RNAseq of isolated RNA from brown adipose tissue and thyroid tissue of 15 new-born Romney lambs, exposed to cold (4°C, n=6) or ambient conditions (20-22°C, n=6) for two days. A control group was utilized as baseline for analysis (n=3), where tissues were collected at around 24 h after lambing.