Developmental skills, measured by the MSCA in a population of eight-year-old children with DS (n = 285), compared to the normative sample (NS, n = 238); raw scale scores are reported; higher scores denote more favorable skills.

*p**p***p1Cohen's d effect size: ddddd≥1.3 very large.Abbreviations: MSCA – McCarthy Scales of Children's Ability, DS – Down syndrome, NS – Normative sample, SD – standard deviation.