Transcriptome Analysis Reveals the Immune Network of Phytophthora infestans effector Pi07586 Inhibiting the Defense Response of Potato

Phytophthora infestans is one of the most severe plant oomycete pathogens, which had caused late blight to potatoes worldwide. The successful infection of P. infestans secretes a repertoire of effectors into host cells to manipulate host immunity. For the majority of effectors, the mechanisms related to how they alter the expression of host genes and reprogram defenses are not clear. Here, an effector Pi07586 has been implicated in the suppression of host immunity. Pi07586 was highly up-regulated in the early stage of infection and localized in the cell nucleus. Overexpression of Pi07586 enhanced leaf colonization by P. infestans. RNA-seq analysis revealed that Pi07586 significantly inhibited the expression of PR-1C-like and photosynthetic antenna protein genes. Nevertheless, ERF1B-like and ERF096-like negative regulation of plant disease resistance.