Infection with Hepatitis C Virus Depends on TACSTD2, a Regulator of Claudin-1 and Occludin Highly Downregulated in Hepatocellular Carcinoma [cell line]. Homo sapiens
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https://www.ncbi.nlm.nih.gov/bioproject/PRJNA313407
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资源简介:
Our study identifies TACSTD2 as a novel regulator of two major HCV entry factors, CLDN1 and OCLN, which is strongly downregulated in malignant hepatocytes. These results provide new insights into the complex process of HCV entry into hepatocytes and may assist in the development of more efficient cellular systems for HCV propagation in vitro. Overall design: Microarrays were performed on Huh7.5 and HepG2 cell lines maintained in Dulbecco’s modified Eagle’s medium (DMEM) with 10% FBS and 2mM L-glutamine.
创建时间:
2016-02-29



