Che-1 is targeted by c-Myc to sustain proliferation in pre-B-cell acute lymphoblastic leukemia [RNA-seq]. Homo sapiens

This Series contain trascriptional profiling via RNA-seq for two ALL-B cell lines, one commercial (NALM-6), one patient-derived (LAL-B), in presence or absence of AATF transcript. In NALM-6, also MYC was depleted and sequenced in triplicate. Furthermore, the Burkitt's Lymphoma P493 cell line has been sequenced in presence or absence of Tetracycline (MYC On-Off) and in CN vs siAATF. Overall design: RNA-seq of B-cell cell lines after knockdown of Che-1/AATF or MYC. The submitter declares that the raw data for the LAL-B cell line Samples (GSM2459108-GSM2459113) will be made available in dbGaP (https://www.ncbi.nlm.nih.gov/gap) due to patient privacy concerns.