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BRCA1 mutational complementation induces synthetic viability

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NIAID Data Ecosystem2026-03-11 收录
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We report DNA resection length after induced double stranded breaks in specific genomic loci with the expression of the AsisI restriction enzyme Overall design: Exponentially AsiSI-expressing MEFs with different Brca1 alleles were treated with 1uM doxocyclin (DOX) for 24 hours and then, for 5 hours with 4-OHT, resulting in the nuclear translocation of AsiSI BRCA1 alleles used in this study: CC: Deletion 4287 to 4295 Del 11: Deletion 874 to 4188

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2020-03-25
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