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Identification of HOXB13 target genes responsive to BET inhibitors

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NIAID Data Ecosystem2026-05-26 收录
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We identified BRD4 as an epigenetic regulator of the prostate lineage specific gene HOXB13 during progression of the disease from an androgen dependent to an androgen independent state. Overall design: Integrative analysis- we compared genes whose expression was significantly impacted either (up or downregulated) as a result of HOXB13 knockdown and were also sensitive to BET inhibition

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2019-03-02
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