Structure of the thermostalilized EAAT1 cryst-II mutant in complex with L-ASP and the allosteric inhibitor UCPH101
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Structure of the thermostalilized EAAT1 cryst-II mutant in complex with L-ASP and the allosteric inhibitor UCPH101 Descriptor: 2-Amino-5,6,7,8-tetrahydro-4-(4-methoxyphenyl)-7-(naphthalen-1-yl)-5-oxo-4H-chromene-3-carbonitrile, ASPARTIC ACID, Excitatory amino acid transporter 1,Neutral amino acid transporter B(0),Excitatory amino acid transporter 1, ... Authors: Canul-Tec, J, Assal, R, Legrand, P, Reyes, N. Deposit date: 2016-07-29 Release date: 2017-04-19 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (3.1 Å) Cite: Structure and allosteric inhibition of excitatory amino acid transporter 1. Nature, 544, 2017
热稳定化EAAT1（Excitatory amino acid transporter 1）cryst-II突变体与L-天冬氨酸（L-ASP）及变构抑制剂UCPH101的复合物结构 描述项：2-氨基-5,6,7,8-四氢-4-(4-甲氧基苯基)-7-(1-萘基)-5-氧代-4H-色烯-3-甲腈、天冬氨酸、兴奋性氨基酸转运体1（Excitatory amino acid transporter 1，EAAT1）、中性氨基酸转运体B(0)、兴奋性氨基酸转运体1（EAAT1）…… 作者：Canul-Tec J、Assal R、Legrand P、Reyes N 提交日期：2016-07-29 发布日期：2017-04-19 最后修改日期：2024-01-10 实验方法：X射线衍射（分辨率3.1 Å） 引用文献：《兴奋性氨基酸转运体1的结构与变构抑制机制》，《自然》（*Nature*），544卷，2017年
