Sleep EEG-fMRI Project

Sleep EEG-fMRI Project Data overviewSleep is a fundamental physiological necessity for rejuvenating optimal brain function and maintaining metabolic health. Yet, its underlying mechanisms remain elusive in humans. Simultaneous EEG-fMRI combines both electrophysiology’s high temporal resolution and fMRI’s high spatial resolution, which together characterize spatiotemporal dynamics in brain function during sleep. Here, we present a comprehensive dataset of sleep EEG-fMRI data from 130 healthy adults with a total duration of over 370 hours in nocturnal sleep, capturing all five physiological stages. Remarkably, we were able to obtain stable rapid eye movement (REM) sleep data from 23 participants, which is unprecedented in the sleep EEG-fMRI literature. This resource of EEG-fMRI data will accelerate theoretical studies of sleep mechanisms, EEG and fMRI methodological studies, and establish a reference for understanding sleep-related mental disorders. Sleep EEG-fMRI dataset includes high-resolution T1-weighted structural MR images and BOLD fMRI data simultaneously acquired with EEG during nocturnal sleep. The sleep EEG-fMRI scan started around midnight and ended around 3 AM. Sleep stages were scored every 30 seconds by an experienced technician based on EEG data according to the AASM criteria. One hundred and twenty-nine out of the 130 participants (99.23%) fell asleep with at least one 30-second epoch, with an average sleep duration of 2.17 hours. Sleep diary, sleep questionnaires, cognitive tests, and whole-night sleep recordings of the participants were also acquired and shared.  Data summaryParticipants: 130 healthy young adultsImaging scanner: 3T MR (Siemens Prisma)EEG: 64-channel caps with EEG, ECG, EMG, and EOG (Brain Products)Institution: Peking University, Beijing, ChinaFunding agencies: The STI2030-Major Projects; National Natural Scientific Foundation of China; Collaborative Research Fund of Chinese Institute for Brain Research, Beijing; and Beijing United Imaging Research Institute of Intelligent Imaging Foundation.  To access the data, investigators must complete the application file, i.e., the Data Use Agreement on the Sleep EEG-fMRI Project and have it reviewed and approved by the PIs of the project (Drs. Jia-Hong Gao and Qihong Zou). All terms specified by the Data Use Agreement on the Sleep EEG-fMRI Project must be complied with. Requests for further information and collaboration are encouraged and will be considered by the Sleep EEG-fMRI Project. We encourage you to read the Data Use Agreement and contact us via [e-mail] and [e-mail].