Though DNMTs inhibitors were widely used in myelodysplastic syndrome and leukaemia, their application in solid tumours has been limited by low response rate and lack of optimal combination strategies.
This study investigate PDAC resistance to paclitaxel. Comparative gene expression profiling analysis of RNA-seq data for Patu-T, Suit.2-028 and Patu-T and Suit.2-028 resistant to gemcitabine or paclit
Here we show how the cardiac transcriptome evolves during murine myocarditis revealing early and persistent activation of cytokine and chemokine-signalling pathways together with innate immune, antige