Supplementary Files

Supplementary Microsoft Excel files containing extended data that is referenced in the text.<br>These include:<b>File 1</b>: Select proteins’ 30MY ERC lists, contains multiple-test corrected p-values. <b>File 2</b>: Pairwise ρ and unadjusted p-value 30MY ERC matrices for all proteins. <b>File 3</b>: Enrichment results for select top ERC protein sets. <b>File 4</b>: Zip file containing the mammalian time-scaled phylogeny and maximum likelihood protein trees in newick format. <b>File 5</b>: Table depicting the total number of taxa present for each protein’s sequence data, along with the number of taxa for which there are paralogy in the uncorrected and 30MY corrected data. <b>File 6</b>: Branch time to terminal branch rate correlation results for the protein set. <b>File 7</b>: Chi-squared test results for all proteins testing for whether there is an overrepresentation of rates below the regression line for short branches (&lt;30MY). <b>File 8</b>: Branch time vs terminal branch rate residuals to branch time correlation results for the protein set. <b>File 9</b>: Wilcoxon matched signed-rank test significance values testing for branch adjustments following 20MY and 30MY adjustments. <b>File 10</b>: Coefficients for the select proteins used for the linear models containing ACE2 rate rank, Btime rate rank, and taxonomic orders as independent variables. <b>File 11</b>: 30MY-adjusted ERC comparisons within and between CORUM complex members.