Test Quality Metrics for SPr and CD Assays for Asymmetric Self-Renewal.

% ASYM Pattern, percent of evaluated sister cell pairs or sister nuclei pairs showing an asymmetric protein expression pattern; ASYM, under conditions that promote asymmetric self-renewal; SYM under conditions that promote symmetric self-renewal; n, number of pairs randomly evaluated under each condition for two independent assays; p, Fisher's exact test for the statistical confidence of specific asymmetric pattern detection vs. symmetric pattern detection; Sen, test sensitivity; Spe, test specificity; PPV, test positive predictive value.