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Wild Type HIV-1 Protease with potent Antiviral inhibitor GRL-98065

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Protein Data Bank Japan2023-11-01 更新2026-03-21 收录
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https://pdbj.org/mine/summary/2z4o
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Wild Type HIV-1 Protease with potent Antiviral inhibitor GRL-98065 Descriptor: (3R,3AS,6AR)-HEXAHYDROFURO[2,3-B]FURAN-3-YL(2S,3R)-3-HYDROXY-4-(N-ISOBUTYLBENZO[D][1,3]DIOXOLE-5-SULFONAMIDO)-1-PHENYLBUTAN-2-YLCARBAMATE, ACETATE ION, CHLORIDE ION, ... Authors: Wang, Y.F, Tie, Y, Boross, P.I, Tozser, J, Ghosh, A.K, Harrison, R.W, Weber, I.T. Deposit date: 2007-06-20 Release date: 2008-04-22 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (1.6 Å) Cite: Potent new antiviral compound shows similar inhibition and structural interactions with drug resistant mutants and wild type HIV-1 protease. J.Med.Chem., 50, 2007
创建时间:
2007-06-20
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