Brain development from infancy to adulthood following very preterm birth

Adverse experiences and events during the fetal and neonatal period, the most dynamic period of brain development, can profoundly influence lifelong health and well-being. This thesis investigated the consequences of being born very preterm on brain development from infancy to adulthood, through five studies involving brain imaging methods. It was found that very preterm birth impairs brain development over childhood, leading to long-lasting, amplified brain abnormalities years later, which are related to cognitive difficulties. The knowledge base generated will aid with future research and translational studies to support and improve developmental outcomes for all children.