The stereochemical configurations at the C2 and C6 carbons of hydroxynorketamine (HNK) affect the concentration-dependent decrease in intracellular D-Ser concentration in PC-12 cells.
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The relative pharmacological activity (αD) is derived by IC50(trans-isomer)/IC50(cis-isomer). The IC50 values are expressed as means ± SD, n = 3 independent experiments.
创建时间:
2016-04-25




