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Transient commensal clonal interactions can drive tumor metastasis

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NIAID Data Ecosystem2026-03-12 收录
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Intratumoral heterogeneity is well-recognized but its impact on tumor progression is unclear. Here, we derived unbiased clonal populations from OCI-C5x, a patient-derived ovarian clear cell carcinoma cell line, and assessed their tumorigenicity and tracked their fate during tumor progression. Results provide insight into intratumoral heterogeneity of clear cell carcinoma mutational landscapes.

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2020-10-26
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